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There are two different Rpi enzymes, RpiA and RpiB, with little sequence or structural similarity and distinct mechanisms

Adults with obesity or significant excess weight who have not found sustainable results through diet and exercise alone, and who are open to discussing prescription options with a licensed clinician, represent the population Novi's program is designed to serve

Most patients experience some discomfort after the fat removal procedure for a few days

The initiative includes onboarding assistance, device counselling, injection training, tele-support, and adherence monitoring through a digital platform

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These are signals, not definitive conclusionsbut they come directly from patients and may deserve further attention, said lead author Neil Sehgal